Scientifica IVM Triple
A pioneering three axis motorized manipulator flawlessly designed for challenging in-vivo electrophysiology recordings.
A versatile three axis motorised manipulator that enables precise, controlled positioning of pipettes and probes, including multielectrode recording technologies such as Neuropixels probes and microelectrode arrays. Perfect for a range of electrophysiology experiments, including field recordings and patch clamp, as well as microinjection experiments.
The IVM Triple is compatible with all common stereotaxic frames and breadboard mounts. The long travel and ultra-smooth motion of all three axis make this micromanipulator the perfect solution for in vivo experiments, stereotaxic surgical procedures and microinjections including dyes and fluorescent probes.
Maximises tissue health
Smooth probe insertion into the brain. Using the unique 'creeper' function to precisely control the movement of the manipulator, your probe can 'creep', driving your experiment to the desired position. This minimises tissue damage during insertion, reduces gliosis and increases the signal quality and data you receive from neurons.
Accurate and stored memory positioning
Hit your precise target every time by programming the IVM triple to move to the exact brain region you are interested in, at a speed of your choice, with the freedom to add an unlimited number of stored memory positions. The IVM triple has 20 nm resolution for absolute positioning.
Perform long-term experiments
The high stability and low drift of the design ensures you can maintain position in the brain for reliable, long-term experiments.
Reach deep into your sample
The 70mm of travel allows easy access to deep tissue in larger in vivo preparations, enabling all areas of the brain to be reached, as well as allowing you to move the manipulator out of the way for positioning the animal.
High signal-to-noise ratio
The smooth approach minimises tissue damage, maximises the signal-to-noise ratio and improves histological outcomes. The shielded electronics and built-in grounding allow sensitive recordings such as single channel recordings.
Focus on your sample
The hands-free movement allows you to concentrate on the welfare of your sample during probe positioning. The risk of human error is minimised, saving time and biological replicates, increasing your experimental efficiency.
The continuous, smooth motion of the manipulator means minimal vibrations compared to the stop-start motion of a manual manipulator. This improves accuracy and reduces damage, so you can draw reliable conclusions from your results.
Easy probe positioning
The adjustable approach in the Z angle, means you can easily alter your approach angle, maintaining accuracy and ensuring you reach your area of interest.
The IVM Triple is compatible with all common stereotaxic frames and breadboard mounts, making the IVM Triple an easy addition to existing equipment.
Advanced control options
Operate the IVM Triple using our ergonomically designed configurable control options or through our specially designed and customisable LinLab software.
The creeper function in LinLab allows the movement of the manipulator to be programmed over a set distance at a pre-defined speed. This allows for smooth motion to the correct area of interest.
Alternatively, the step function can be used for faster, yet measured step movement to insert the electrode into the cell.
Position co-ordinates can be viewed, stored, exported and recalled in LinLab, or users can couple the system with our PatchPad Display Controller, so X, Y and Z co-ordinates can be viewed in real time right by the sample. An ideal set up for customers doing auditory research who wish to avoid using a workstation near to their sample.
In vivo electrophysiology
- Blind patch clamp
- Field recordings
- Whole cell recordings
In vivo microinjection
- Viral injection
- Fluorophore injection
- Neural implants
- Optical fibres
"Compared to other micromanipulators I have used, the Scientifica IVM allows us to isolate more cells and to record from each cell for a longer time."Dr Nicholas Lesica Ear Institute, University College London
- Watch on-demand: Advancements in multielectrode recording techniques in neurophysiology
- SciMethods: Paired Blind Polytrode and Juxtacellular Recordings In Vivo
- #LabHacks: How to reduce the noise around your electrophysiology rig
- #LabHacks: Tips for improving your electrophysiology experiments
- Advice for ensuring your equipment is sterile to reduce the spread of COVID-19
Speak to one of our experts for details on pricing, features, installation and support.