Scientifica IVM Single

Scientifica IVM Single

Ensure maximum tissue health when reliably positioning electrophysiological and microinjection probes in your sample.

This super-smooth, stereotaxic motorised manipulator enables you to precisely position your pipettes and probes. Designed for multielectrode recording (such as Neuropixels probes) in vivo patch clamp electrophysiology, and microinjection. The IVM Single enables you to carry out long, reliable experiments.

The IVM Single is compatible with all common stereotaxic frames making it simple to add to existing set-ups where you require healthy samples and greater control.

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产品优势

Maximises tissue health

Smooth probe insertion into the brain. Using the unique 'creeper' function to precisely control the movement of the manipulator, your probe can 'creep' to the desired position at a speed of your choice. This minimises tissue damage, reduces gliosis and increases the signal quality and data you receive from neurons.

Investigate deep within your sample

The long 70mm range of travel means you have ultimate freedom to position anywhere within your sample.

Maximise sample comfort and attention

The extremely low audible noise of the IVM Single, when in motion or at rest, means your sensitive sample will not be disturbed by audible sounds.

Compatible with all stereotaxic frames

The IVM Single is compatible with whichever stereotaxic frame you choose, giving you flexibility with your choice of experimental setup.

Great resolution

The IVM has 20 nm resolution for absolute positioning. View the exact position of your probe using dedicated software.

Gently position probes to ensure maximal tissue health

The unique “Creeper” function enables you to automatically position your probe - set the position and the speed of movement and let the manipulator do the work.

Confidently record from the exact area of interest

Utilise the positional readout, using the software, to position your probe exactly where you want it to be within the tissue.

Acquire reliable data for the full duration of your experiments

The high stability of the design ensures you can maintain position in the brain or other tissue for reliable, long-term experiments.

Record even the smallest electrophysiological signals

The low-noise electronics and grounding allows smaller signals to be detected and provides cleaner data.

Focus on your sample’s welfare

The hands-free movement and motorised control allows you to concentrate on the welfare of your sample during probe positioning.

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LinLab is a versatile control software designed to give you advanced control over your motorised Scientifica device.

Advanced control options

Operate the IVM Single using our ergonomically designed configurable control options or through our specially designed and customisable LinLab software.

The creeper function in LinLab allows the movement of the manipulator to be programmed over a set distance at a pre-defined speed. This allows for smooth motion to the correct area of interest.

Alternatively, the step function can be used for faster, yet measured step movement to insert the electrode into the cell.

Position co-ordinates can be viewed, stored, exported and recalled in LinLab, so X, Y and Z co-ordinates can be viewed in real time right by the sample. An ideal set up for customers doing auditory research who wish to avoid using a workstation near to their sample.

Downloads

Download the IVM Single brochure for more information.

Ensure maximum tissue health when reliably positioning electrophysiological and microinjection probes in your sample.

Applications

In vivo electrophysiology

- Field recordings

- Whole cell recordings

- Stimulation

In vivo microinjection

- Viral injection

- Fluorophore injection

Positioning

- Neural implants

- Optical fibres

- Cannulae

用户评价

“I used the IVM with a Neuropixels probe and it worked exceptionally well! The IVM integrated well on the stereotaxic frame and it was extremely smooth to put the probe in using 50 and 100 micron steps.”

Dr Daniel Whitcomb
University of Bristol