Scientifica SliceScope Pro 2000
标准系统
We can customise this system to suit your unique experimental needs. Please contact us to discuss your requirements.
Slimline fully motorised microscope
Choose from Scientifica PatchStars or MicroStars
50mm of travel
Large mounting stage for sample & manipulators
Choose from the Scientifica PatchPad or Control Cube
调查报告
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Dopamine and serotonin cotransmission filters striatonigral synaptic activity via 5-HT1B receptor activation
Molinari, M., Aaltonen, A., Lieberman, O. J., Sulzer, D., Santini, E., & Borgkvist, A. (2025). Dopamine and serotonin cotransmission filters striatonigral synaptic activity via 5-HT1B receptor activation. Science Advances, 11(45), eadx4577. https://doi.org/10.1126/sciadv...
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Novel binding mode for negative allosteric NMDA receptor modulators
Yates-Hansen, C. K., & Rau, A. R. (2025b). Novel binding mode for negative allosteric NMDA receptor modulators. The Journal of General Physiology, 158(1). https://doi.org/10.1085/jgp.20...
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Disentangling the effects of corticotrophin releasing factor and GABA release from the bed nucleus of the stria terminalis on ethanol self-administration in mice
Gianessi, C. A., Haun, H. L., Pati, D., Sides, T., D’Ambrosio, S. L., Kelson, W. P., Hernandez, R., Gereau, G. B., Boyt, K., Hodge, C. W., & Kash, T. L. (2025). Disentangling the effects of corticotrophin releasing factor and GABA release from the bed nucleus of the stria terminalis on ethanol self-administration in mice. Neuropsychopharmacology. https://doi.org/10.1038/s41386...
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Characterizing the diversity of layer 2/3 human neocortical neurons in pediatric epilepsy
Kushner, J. K., Hoffman, P. B., Brzezinski, C. R., Svalina, M. N., O’Neill, B. R., Hankinson, T. C., Wilkinson, C. C., Handler, M. H., Baca, S. M., Huntsman, M. M., & Alexander, A. L. (2025). Characterizing the diversity of layer 2/3 human neocortical neurons in pediatric epilepsy. eNeuro, ENEURO.0247-24.2025. https://doi.org/10.1523/ENEURO.0247-24.2025
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Visualization of gap Junction–Mediated astrocyte coupling in acute mouse brain slices
Kompier, N. F., Siemonsmeier, G., Meyer, N., Kettenmann, H., & Rathjen, F. G. (2025). Visualization of gap Junction–Mediated astrocyte coupling in acute mouse brain slices. BIO-PROTOCOL, 15(1365). https://doi.org/10.21769/biopr...
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A bistable inhibitory optoGPCR for multiplexed optogenetic control of neural circuits
Wietek, J., Nozownik, A., Pulin, M., Saraf-Sinik, I., Matosevich, N., Gowrishankar, R., Gat, A., Malan, D., Brown, B. J., Dine, J., Imambocus, B. N., Levy, R., Sauter, K., Litvin, A., Regev, N., Subramaniam, S., Abrera, K., Summarli, D., Goren, E. M., . . . Yizhar, O. (2024). A bistable inhibitory optoGPCR for multiplexed optogenetic control of neural circuits. Nature Methods, 21(7), 1275–1287. https://doi.org/10.1038/s41592...
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Synaptic dysfunction by mutations in GRIN2B: Influence of triheteromeric NMDA receptors on Gain-of-Function and Loss-of-Function mutant classification
Elmasri, M., Lotti, J. S., Aziz, W., Steele, O. G., Karachaliou, E., Sakimura, K., Hansen, K. B., & Penn, A. C. (2022). Synaptic dysfunction by mutations in GRIN2B: Influence of triheteromeric NMDA receptors on Gain-of-Function and Loss-of-Function mutant classification. Brain Sciences, 12(6), 789. https://doi.org/10.3390/brains...
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Histone Methylation by the Kleefstra Syndrome Protein EHMT1 Mediates Homeostatic Synaptic Scaling
Benevento, M., Iacono, G., Selten, M., Ba, W., Oudakker, A., & Frega, M. et al. (2016). Histone Methylation by the Kleefstra Syndrome Protein EHMT1 Mediates Homeostatic Synaptic Scaling. Neuron, 91(2), 341-355. http://dx.doi.org/10.1016/j.ne...
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Divergent Routing of Positive and Negative Information from the Amygdala during Memory Retrieval
Beyeler, A., Namburi, P., Glober, G., Simonnet, C., Calhoon, G., & Conyers, G. et al. (2016). Divergent Routing of Positive and Negative Information from the Amygdala during Memory Retrieval. Neuron, 90(2), 348-361. http://dx.doi.org/10.1016/j.ne...
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Amygdala inputs to prefrontal cortex guide behavior amid conflicting cues of reward and punishment
Burgos-Robles, A., Kimchi, E., Izadmehr, E., Porzenheim, M., Ramos-Guasp, W., & Nieh, E. et al. (2017). Amygdala inputs to prefrontal cortex guide behavior amid conflicting cues of reward and punishment. Nature Neuroscience. http://dx.doi.org/10.1038/nn.4...
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Tuning of fast-spiking interneuron properties by an activity-dependent transcriptional switch
Dehorter, N., Ciceri, G., Bartolini, G., Lim, L., del Pino, I., & Marin, O. (2015). Tuning of fast-spiking interneuron properties by an activity-dependent transcriptional switch. Science, 349(6253), 1216-1220. http://dx.doi.org/10.1126/scie...
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Marking cells with infrared fluorescent proteins to preserve photoresponsiveness in the retina
Fyk-Kolodziej, B., Hellmer, C., & Ichinose, T. (2014). Marking cells with infrared fluorescent proteins to preserve photoresponsiveness in the retina. Biotechniques, 57(5). http://dx.doi.org/10.2144/0001...
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A group I metabotropic glutamate receptor controls synaptic gain between rods and rod bipolar cells in the mouse retina
Hellmer, C., Clemons, M., Nawy, S., & Ichinose, T. (2018). A group I metabotropic glutamate receptor controls synaptic gain between rods and rod bipolar cells in the mouse retina. Physiological Reports. https://physoc.onlinelibrary.w...
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Morphological and physiological analysis of type-5 and other bipolar cells in the Mouse Retina
Hellmer, C., Zhou, Y., Fyk-Kolodziej, B., Hu, Z., & Ichinose, T. (2016). Morphological and physiological analysis of type-5 and other bipolar cells in the Mouse Retina. Neuroscience, 315, 246-258. http://dx.doi.org/10.1016/j.ne...
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Dopaminergic Modulation of Signal Processing in a Subset of Retinal Bipolar Cells
Hellmer, C., Bohl, J., Hall, L., Koehler, C., & Ichinoise, T. (2020). Dopaminergic Modulation of Signal Processing in a Subset of Retinal Bipolar Cells. Frontiers in Cellular Neuroscience. https://doi.org/10.3389/fncel.2020.00253
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Differential signalling and glutamate receptor compositions in the OFF bipolar cell types in the mouse retina
Ichinose, T., & Hellmer, C. (2015). Differential signalling and glutamate receptor compositions in the OFF bipolar cell types in the mouse retina. The Journal Of Physiology, 594(4), 883-894. http://dx.doi.org/10.1113/jp27...
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Dopamine D1 receptor expression is bipolar cell type-specific in the mouse retina
Ichinose, T., Farshi, P., Fyk-Kolodziej, B., Krolewski, D., & Walker, P. (2015). Dopamine D1 receptor expression is bipolar cell type-specific in the mouse retina. The Journal Of Comparative Neurology, 524(10). Retrieved from http://onlinelibrary.wiley.com...
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Roles of ON Cone Bipolar Cell Subtypes in Temporal Coding in the Mouse Retina
Ichinose, T., Fyk-Kolodziej, B., & Cohn, J. (2014). Roles of ON Cone Bipolar Cell Subtypes in Temporal Coding in the Mouse Retina. Journal Of Neuroscience, 34(26), 8761-8771. http://dx.doi.org/10.1523/jneu...
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ATP P2X Receptors Downregulate AMPA Receptor Trafficking and Postsynaptic Efficacy in Hippocampal Neurons
Pougnet, J., Toulme, E., Martinez, A., Choquet, D., Hosy, E., & Boué-Grabot, E. (2014). ATP P2X Receptors Downregulate AMPA Receptor Trafficking and Postsynaptic Efficacy in Hippocampal Neurons. Neuron, 83(2), 417-430. http://dx.doi.org/10.1016/j.ne...
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Age-dependent changes of photosynthetic responses induced by electrical signals in wheat seedlings
Vodeneev, V., Sherstneva, O., Surova, L., Semina, M., Katicheva, L., & Sukhov, V. (2016). Age-dependent changes of photosynthetic responses induced by electrical signals in wheat seedlings. Russian Journal Of Plant Physiology, 63(6), 861-868. http://dx.doi.org/10.1134/s102...
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Glucose concentrations modulate brain‐derived neurotrophic factor responsiveness of neurones in the paraventricular nucleus of the hypothalamus
McIsaac, W., Ferguson, A V. (2017). Glucose concentrations modulate brain‐derived neurotrophic factor responsiveness of neurones in the paraventricular nucleus of the hypothalamus. Journal of Neuroendocrinology, 29(4). https://onlinelibrary.wiley.com/doi/full/10.1111/jne.12464