Scientifica SliceScope Pro 1000

调查报告

• EphB1-NR2B receptor signaling in glutamatergic neurons of the ventroposteromedial thalamic nucleus regulates emergence from anesthesia

  Liu, Y., Hu, J., Cao, B., Chen, P., Peng, B., Yao, H., & Song, X. (2025b). EphB1-NR2B receptor signaling in glutamatergic neurons of the ventroposteromedial thalamic nucleus regulates emergence from anesthesia. Science Advances, 11(49). https://doi.org/10.1126/sciadv...

• Disrupted theta synchronization and synaptic connectivity in the visual cortex of Fmr1 KO mice

  Cheng, X., Nareddula, S., Gao, H., Chen, Y., Xiao, T., Nadew, Y. Y., Xu, F., Edens, P. A., Saldarriaga, V., Hu, X., Quinn, C. J., Kimbrough, A., Huang, F., Chubykin, A. A., Cheng, X., Nareddula, S., Gao, H., Chen, Y., Xiao, T., . . . Chubykin, A. A. (2025b). Disrupted theta synchronization and synaptic connectivity in the visual cortex of Fmr1 KO mice. Nature Communications, 16(1). https://doi.org/10.1038/s41467...

• Neuronal activity-dependent mechanisms of small cell lung cancer pathogenesis

  Savchuk, S., Gentry, K. M., Wang, W., Carleton, E., Biagi-Junior, C. a. O., Luthria, K., Yalçın, B., Ni, L., Farnsworth, H. C., Davis, R. A., Drexler, R., Melms, J. C., Liu, Y., Acosta-Alvarez, L., Hartmann, G. G., Pavarino, E. C., LaBelle, J., Woo, P. J., Toland, A. M., . . . Venkatesh, H. S. (2025). Neuronal activity-dependent mechanisms of small cell lung cancer pathogenesis. Nature, 646(8087), 1232–1242. https://doi.org/10.1038/s41586...

• Blue-shifted ancyromonad channelrhodopsins for multiplex optogenetics

  Elena G Govorunova, Oleg A Sineshchekov, Hai Li, Yueyang Gou, Hongmei Chen, Shuyuan Yang, Yumei Wang, Stephen Mitchell, Alyssa Palmateer, Leonid S Brown, François St-Pierre, Mingshan Xue, John L Spudich (2025) Blue-shifted ancyromonad channelrhodopsins for multiplex optogenetics eLife 14:RP106508 https://doi.org/10.7554/eLife....

• Excitatory and inhibitory neurotransmitter alterations with advancing age and injury in the mouse retina

  Bell, K.C. et al. (2025) 'Excitatory and inhibitory neurotransmitter alterations with advancing age and injury in the mouse retina,' Neurobiology of Aging, 150, pp. 69–79. https://doi.org/10.1016/j.neur....

• Microcircuit failure in STXBP1 encephalopathy leads to hyperexcitability

  Santos, A. B. D., Larsen, S. D., Guo, L., Barbagallo, P., Montalant, A., Verhage, M., Sørensen, J. B., & Perrier, J. (2023). Microcircuit failure in STXBP1 encephalopathy leads to hyperexcitability. Cell Reports Medicine, 4(12), 101308. https://doi.org/10.1016/j.xcrm...

• High sucrose consumption decouples intrinsic and synaptic excitability of AgRP neurons without altering body weight.

  Korgan, A.C., Oliveira-Abreu, K., Wei, W. et al. High sucrose consumption decouples intrinsic and synaptic excitability of AgRP neurons without altering body weight. (2023) International Journal of Obesity 47, 224–235. https://doi.org/10.1038/s41366...

• Impaired pre-synaptic plasticity and visual responses in auxilin-knockout mice

  Cheng, X., Tang, Y., Vidyadhara, D., Li, B., Zimmerman, M., Pak, A., Nareddula, S., Edens, P. A., Chandra, S. S., & Chubykin, A. A. (2023). Impaired pre-synaptic plasticity and visual responses in auxilin-knockout mice. iScience, 26(10), 107842. https://doi.org/10.1016/j.isci...

• Oxytocin excites BNST interneurons and inhibits BNST output neurons to the central amygdala.

  Walter Francesconi, Fulvia Berton, Valentina Olivera-Pasilio, Joanna Dabrowska. (2021). Oxytocin excites BNST interneurons and inhibits BNST output neurons to the central amygdala. Neuropharmacology, 192. https://doi.org/10.1016/j.neuropharm.2021.108601

• Profound Desensitization by Ambient GABA Limits Activation of δ-Containing GABAA Receptors during Spillover.

  Damian P. Bright, Massimiliano Renzi, Julian Bartram, Thomas P. McGee, Georgina MacKenzie, Alastair M. Hosie, Mark Farrant and Stephen G. Brickley. (2011). Profound Desensitization by Ambient GABA Limits Activation of δ-Containing GABAA Receptors during Spillover. Journal of Neuroscience, 31 (2) 753-763. https://doi.org/10.1523/JNEURO...

• Gap Junctions Link Regular-Spiking and Fast-Spiking Interneurons in Layer 5 Somatosensory Cortex.

  Hatch Robert J., Mendis G. Dulini C., Kaila Kai, Reid Christopher A., Petrou Steven. Gap Junctions Link Regular-Spiking and Fast-Spiking Interneurons in Layer 5 Somatosensory Cortex. (2017). Frontiers in Cellular Neuroscience,11. https://doi.org/10.3389/fncel....

• Distinct profiles of functional discrimination among G proteins determine the actions of G protein–coupled receptors.

  Ikuo Masuho and Olga Ostrovskaya and Grant M. Kramer and Christopher D. Jones and Keqiang Xie and Kirill A. Martemyanov. (2015). Distinct profiles of functional discrimination among G proteins determine the actions of G protein–coupled receptors. Science Signaling, 8. DOI: 10.1126/scisignal.aab406

• GABAB receptors modulate Ca2+ but not G protein-gated inwardly rectifying K+ channels in cerebrospinal-fluid contacting neurones of mouse brainstem.

  Jurčić, N., Er-Raoui, G., Airault, C., Trouslard, J., Wanaverbecq, N. and Seddik, R. (2019). GABA_B receptors modulate Ca²⁺ but not G protein-gated inwardly rectifying K channels in cerebrospinal-fluid contacting neurones of mouse brainstem. J Physiol, 597: 631-651. https://doi.org/10.1113/JP277172⁺

• Granular Layer Neurons Control Cerebellar Neurovascular Coupling Through an NMDA Receptor/NO-Dependent System.

  Lisa Mapelli, Giuseppe Gagliano, Teresa Soda, Umberto Laforenza, Francesco Moccia, Egidio U. D'Angelo. Granular Layer Neurons Control Cerebellar Neurovascular Coupling Through an NMDA Receptor/NO-Dependent System. (2017) Journal of Neuroscience, 37 (5) 1340-1351. https://doi.org/10.1523/JNEURO...

• Firing properties of entorhinal cortex neurons and early alterations in an Alzheimer's disease transgenic model.

  Marcantoni, A., Raymond, E.F., Carbone, E. et al. Firing properties of entorhinal cortex neurons and early alterations in an Alzheimer's disease transgenic model. (2014) Pflugers Arch - Eur J Physiol, 466, 1437–1450. https://doi.org/10.1007/s00424...

• Cleaning patch-clamp pipettes for immediate reuse.

  Kolb, I., Stoy, W., Rousseau, E. et al. Cleaning patch-clamp pipettes for immediate reuse. (2016). Sci Rep 6, 35001. https://doi.org/10.1038/srep35...

• Regulator of G-Protein Signaling 7 Regulates Reward Behavior by Controlling Opioid Signaling in the Striatum.

  Laurie P. Sutton, Olga Ostrovskaya, Maria Dao, Keqiang Xie, Cesare Orlandi, Roy Smith, Sunmee Wee, Kirill A. Martemyanov. (2015). Regulator of G-Protein Signaling 7 Regulates Reward Behavior by Controlling Opioid Signaling in the Striatum. Biological Psychiatry, 8, 235-245. https://doi.org/10.1016/j.biopsych.2015.07.026

• Olfactory bulb acetylcholine release dishabituates odor responses and reinstates odor investigation.

  Ogg, M.C., Ross, J.M., Bendahmane, M. et al. Olfactory bulb acetylcholine release dishabituates odor responses and reinstates odor investigation. Nat Commun 9, 1868 (2018). https://doi.org/10.1038/s41467...

• Down-sizing of neuronal network activity and density of presynaptic terminals by pathological acidosis are efficiently prevented by Diminazene Aceturate.

  Roberta de Ceglia, Linda Chaabane, Emilia Biffi, Andrea Bergamaschi, Giancarlo Ferrigno, Stefano Amadio, Ubaldo Del Carro, Nausicaa Mazzocchi, Giancarlo Comi, Veronica Bianchi, Stefano Taverna, Lia Forti, Patrizia D’Adamo, Gianvito Martino, Andrea Menegon, Luca Muzio. Down-sizing of neuronal network activity and density of presynaptic terminals by pathological acidosis are efficiently prevented by Diminazene Aceturate. (2015). Brain, Behavior, and Immunity, 45, 263-276. https://doi.org/10.1016/j.bbi.....

• Scanning Ultrasound (SUS) Causes No Changes to Neuronal Excitability and Prevents Age-Related Reductions in Hippocampal CA1 Dendritic Structure in Wild-Type Mice.

  Robert John Hatch, Gerhard Leinenga, Jürgen Götz. Scanning Ultrasound (SUS) Causes No Changes to Neuronal Excitability and Prevents Age-Related Reductions in Hippocampal CA1 Dendritic Structure in Wild-Type Mice. (2016). PLOS ONE. https://doi.org/10.1371/journal.pone.0164278

• Near-Perfect Synaptic Integration by Nav1.7 in Hypothalamic Neurons Regulates Body Weight.

  Tiago Branco, Adam Tozer, Christopher J. Magnus, Ken Sugino, Shinsuke Tanaka, Albert K. Lee, John N. Wood, Scott M. Sternson. (2016). Near-Perfect Synaptic Integration by Nav1.7 in Hypothalamic Neurons Regulates Body Weight. Cell, 165, 1749-1761. https://doi.org/10.1016/j.cell...

• Setdb1 Histone Methyltransferase Regulates Mood-Related Behaviors and Expression of the NMDA Receptor Subunit NR2B.

  Yan Jiang, Mira Jakovcevski, Rahul Bharadwaj, Caroline Connor, Frederick A. Schroeder, Cong L. Lin, Juerg Straubhaar, Gilles Martin and Schahram Akbarian. Setdb1 Histone Methyltransferase Regulates Mood-Related Behaviors and Expression of the NMDA Receptor Subunit NR2B. (2010). Journal of Neuroscience, 30 (21) 7152-7167. https://doi.org/10.1523/JNEURO...