Molecular Devices MultiClamp 700B Amplifier

A microelectrode amplifier that combines leading edge electronics design and a wealth of features and functions with an intuitive user interface that simplifies the creation of complex protocols.

For single-channel recordings, whole-cell voltage- and current-clamp recordings, intracellular sharp electrode recordings, extracellular field potential recordings in ion channel, neuroscience, nanopore and voltammetry studies

Support of up to four headstages

Makes the MultiClamp 700B System four amplifiers in one

Software control of all amplifier settings

Automated optimization features; reduction of manipulation steps; and convenient; reliable telegraphing

Fast, reproducible application switching

Quick Select Feature recalls up to three saved amplifier configurations

Easy monitoring of membrane and cell health parameters

Integrated seal test in voltage- and current-clamp mode

Dual Command Potential

Add flexibility by processing input signals from two different sources

Flexible

Selectable command sensitivity for flexible control of the output waveform.

Pipette offset compensation with auto-mode quickly removes signal offsets.

Automatic pipette capacitance

Automatic pipette capacitance compensation requires only the push of a button to neutralize the contribution of the glass pipette and the pipette holder to the capacitance of the circuitry.

Series resistance compensation: Prediction helps achieve the desired command level faster by transiently supercharging the membrane potential.

Series resistance compensation

Correction improves the bandwidth of the recording by eliminating the error introduced by the voltage drop across the series resistance.

Automatic cell capacitance compensation corrects for the capacitance of the cell membrane in whole-cell recordings with a single mouse click.

External Control

Automatic mode switching enables you to control the transition between voltage and current clamp by an external trigger or depending on the recorded signal.

Automatic oscillation detection prevents damage to a cell when electrical feedback occurs.

Automatic correction

Leak subtraction for automatic correction of leak currents with a smart, software-based algorithm.

Selectable output gain with 11 settings to scale the output signal to the desired level.

Audio monitor

Audio monitor for acoustic tracking of the signal while you are busy looking down a microscope.

Fine tunable 4-pole bessel and butterworth low-pass filters act as anti-aliasing filters and can be used to pre-condition the output signal.

Additional Resources

Molecular Devices Multiclamp 700b amplifier datasheet

Dimensions (in.)	Dimensions (in.) 3.5 (H)x 19 (W) x 12 (D)
Dimensions (cm)	Dimensions (cm) 8.9 H) x 48.3 (W) x 30.5 (D)
Weight	Weight 10 lbs. (4.54 kg)
Headstage (in.)	Headstage (in.) 0.875 (H) x 1.625(W) x 2.3125 (D)
Headstage (cm)	Headstage (cm) 2.0 (H) x 4.0 (W) x 8.4 (D)
Channels	Channels 2 (sharing a common ground)
Communications	Communications USB 1 Type B female ports
Rack use	Rack use Standard 19" rack-mount (2U) with handles
Benchtop use	Benchtop use Bayonet feet
Power	Power 85-260 VAC, 50-60 Hz, 30 W (max)
Safety	Safety CE marking (Conformité Européenne)