npi electronic VA-10M
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npi electronic VA-10M

A sensitive (picoampere range) current amplifier that is intended for voltammetric and amperometric measurements with carbon-fiber microelectrodes.

Ideal for recordings from single cells.

npi electronic VA-10M
Low noise, works in picoampere range

Can be operated with external waveforms for cyclic voltammetry

Telegraph outputs for easy interfacing to data acquisition systems

3-electrode headstage for a floating command potential available

Gain settings from 0.5 to 50 mV / pA in seven steps

Allows simultaneous electrophysiological recordings during voltammetric or amperometric investigations using headstages with differential inputs

Can be used in scanning electrochemical microscopy.

Also suitable for lipid bilayer recordings.

Use with 5 µm carbon fiber electrodes also available from npi.

Also available as 19" rackmount device.

Headstage
Headstage
Input voltage range: ±1200 mV
Operating voltage: ±12 V
Enclosure: Size: 40 x 70 x 20 mm, not grounded
Mounting plate: 50 x 70 mm, not conducting
Electrode connector: BNC with driven shield
Ground connector: 1 mm connector (black)
Driven shield output: 1 mm connector (red)
Input resistance: >1013 Ω
Current range: ±20 nA
Feedback resistor: 500 MΩ
Noise
Noise
<1 pA
LP filter
LP filter
4-pole or 8-pole Bessel filter, 6 corner frequencies: 100, 300 500, 1k, 3k, 5k Hz.
Gain
Gain
6-position rotary switch (x0.5, x1, x2.5, x5, x10, x25) mV / pA
Voltage source
Voltage source
Command voltage set by 10-turn potentiometer, range: (1000 mV, polarity selectable with polarity switch (+, 0, -), display XXXX mV
Outputs
Outputs
Impedance: 250 ω
Filtered: BNC connector, sensitivity selectable with gain switch, filtered with LP Bessel filter
Unfiltered: BNC connector, sensitivity selectable with gain switch
Inputs
Inputs
Resistance: 1 MΩ
Command voltage
Command voltage
Input BNC connector, sensitivity: /10, also displayed
Monitors
Monitors
Impedance: 250 Ω
Gain: BNC connector, 1 V per step, +1 V....+7 V
Command: BNC connector, sensitivity: x10
Power requirements
Power requirements
115/230 V AC, 60/50 Hz, fuse 0.4/0.2 A, slow
Intra-membrane signalling between the voltage-gated Ca2+-channel and cysteine residues of syntaxin 1A coordinates synchronous release

Scientific Reports

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Electroporation followed by electrochemical measurement of quantal transmitter release from single cells using a patterned microelectrode

Lab on a Chip

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High transconductance organic electrochemical transistors

Nature Communications

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