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npi electronic VA-10M
A sensitive (picoampere range) current amplifier that is intended for voltammetric and amperometric measurements with carbon-fiber microelectrodes.
Ideal for recordings from single cells.
Low noise, works in picoampere range
Can be operated with external waveforms for cyclic voltammetry
Telegraph outputs for easy interfacing to data acquisition systems
3-electrode headstage for a floating command potential available
Gain settings from 0.5 to 50 mV / pA in seven steps
Allows simultaneous electrophysiological recordings during voltammetric or amperometric investigations using headstages with differential inputs
Can be used in scanning electrochemical microscopy.
Also suitable for lipid bilayer recordings.
Use with 5 µm carbon fiber electrodes also available from npi.
Also available as 19" rackmount device.
| Headstage | Input voltage range: ±1200 mV |
|---|---|
| Operating voltage: ±12 V | |
| Enclosure: Size: 40 x 70 x 20 mm, not grounded | |
| Mounting plate: 50 x 70 mm, not conducting | |
| Electrode connector: BNC with driven shield | |
| Ground connector: 1 mm connector (black) | |
| Driven shield output: 1 mm connector (red) | |
| Input resistance: >1013 Ω | |
| Current range: ±20 nA | |
| Feedback resistor: 500 MΩ | |
| Noise | <1 pA |
| LP filter | 4-pole or 8-pole Bessel filter, 6 corner frequencies: 100, 300 500, 1k, 3k, 5k Hz. |
| Gain | 6-position rotary switch (x0.5, x1, x2.5, x5, x10, x25) mV / pA |
| Voltage source | Command voltage set by 10-turn potentiometer, range: (1000 mV, polarity selectable with polarity switch (+, 0, -), display XXXX mV |
| Outputs | Impedance: 250 ω |
| Filtered: BNC connector, sensitivity selectable with gain switch, filtered with LP Bessel filter | |
| Unfiltered: BNC connector, sensitivity selectable with gain switch | |
| Inputs | Resistance: 1 MΩ |
| Command voltage | Input BNC connector, sensitivity: /10, also displayed |
| Monitors | Impedance: 250 Ω |
| Gain: BNC connector, 1 V per step, +1 V....+7 V | |
| Command: BNC connector, sensitivity: x10 | |
| Power requirements | 115/230 V AC, 60/50 Hz, fuse 0.4/0.2 A, slow |
Intra-membrane signalling between the voltage-gated Ca2+-channel and cysteine residues of syntaxin 1A coordinates synchronous release
Scientific Reports
Electroporation followed by electrochemical measurement of quantal transmitter release from single cells using a patterned microelectrode
Lab on a Chip