npi electronic BA-Series
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npi electronic BA-Series

Why use an expensive patch clamp amplifier for current clamp experiments? The more economic and accurate instrument is npi’s BA-Series.

Perform intracellular CC recordings in bridge mode, extracellular recordings with high gain, and juxtacellular filling with the BA-03X Intracellular Bridge Mode and Extracellular Amplifier.

npi electronic BA-Series
Wide-bandwidth high impedance amplifier

Designed for intracellular current clamp recordings with sharp microelectrodes, in perforated or tight seal patch configurations as well as for electroporation and iontop

Housed in a 19" rackmount cabinet

Equipped with functions like two ranges for bridge balance, an oscillation shut-off circuit for protecting the preparation, two potential and two current ranges.

The standard bridge amplifier for intracellular current clamp recordings

Having an extended current range this amplifer is also suitable for electroporation of single cells for non-invasive, juxtacellular filling of cells with dyes or plasmids

The BA-03X has additionally high and low pass filters for the recorded potenial, and a potential gain up to 1000. Therefore, it allows extracellular recordings as well.

Accessories

BA-01X – Intracellular Bridge Mode Amplifier

  • True current clamp operation with direct measurement of membrane potential and complete cancellation of series resistance and stray capacitance.
  • Can be used with sharp microelectrodes, or patch pipettes in whole-cell, cell-attached and perforated-patch configuration.
  • Digital displays for current, voltage and electrode resistance.
  • Buzz and electrode clear facility, audio monitor.
  • Oscillation shut-off uni prevents cells from damage.
  • TTL gates stimulus input with ampliture setting by 3-digit potentiometer and digital read-out of holding current.
  • Enhanced (x10) current range for Juxtracellular recordings, electroporation or Iontophoresis.

BA-03X – Intracellular Bridge Mode and Extracellular Amplifier

  • True current clamp operation with direct measurement of membrane potential and complete cancellation of series resistance and stray capacitance.
  • Can be used with sharp mircroelectrodes, or patch pipettes in whole-cell, cell-attached and perforated-patch configuration.
  • Can be used for extracellular recordings of sub millivolt signals as well.
  • Potential Output Gain: 10, 20, 50, 100, 200, 500, 1k
  • Potential Highpass filter: DC: 0.1, 0.3, 0.5, 1, 3, 10, 30, 50, 100, 200, 500, 600, 1k, 3k Hz
  • Potential Lowepass filter: 20, 50, 100, 200, 300, 500, 700, 1k, 1.3k, 2k, 3k, 5k, 8k, 10k, 13k, 20k Hz
  • Current Output Sensitivity: 0.1, 0.2, 0.5, 1, 2, 5, 10V / nA
  • Digital displays for current, voltage and electrode resistance.
  • Buzz and electrode clear facility, audio monitor.
  • Oscillation shut-off unit prevents cells from damage.
  • TTL gates stimulus input with amplitude setting by 3-digit potentiometer and digital read-out of holding current.
  • Enhanced (x10) current range for Juxtracellular recordings, electroporation or Iontophoresis.

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Daily variation in the electrophysiological activity of mouse medial habenula neurones

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